Short Note
The long-term effects of cocaine use make it not worth a try. The leaves of the South American native coca plant are used to make cocaine, a highly addictive stimulant narcotic.
Although it is permissible for medical professionals to use cocaine for legitimate medical procedures, such as local anesthetic during some surgeries, it is prohibited for recreational usage.
Dealers
To boost their earnings, dealers frequently dilute (or “cut”) it with non-psychoactive ingredients like cornstarch, talcum, flour, or baking soda.
Additionally, they could mix cocaine with substances like procaine, a chemically similar local anesthetic, or amphetamine (another psychoactive stimulant).
On another level of cocaine use, some drug users mix heroin and cocaine.
Dopamine
Dopamine, a natural chemical messenger that regulates motivation and reward, is released at higher rates in brain circuits associated with cocaine use.
Dopamine often recycles back into the cell that first released it, cutting off the signal between nerve cells.
Cocaine, on the other hand, stops dopamine from being recycled, leading to a significant buildup in the area between two nerve cells, which stops normal communication.
The brain’s reward circuit is overflowed with dopamine, which powerfully encourages drug-using habits.
Drug usage may cause the reward circuit to adapt, making it less responsive to the drug.
Therefore, in an effort to get the same high and to relieve withdrawal symptoms, users take stronger and more frequent dosages.
Long-term effects of cocaine use
Some long-term health effects of cocaine depend on the method of use and include the following:
Consuming cocaine by mouth
1. Severe bowel decay from reduced blood flow
Smoking cocaine
2. Cough asthma
3. Respiratory distress
4. Higher risk of infections like pneumonia
Snorting cocaine
5. Loss of smell
6. Nosebleeds
7. Frequent runny nose
8. Problems with swallowing
Needle injection of cocaine
Higher risk for contracting:
9. HIV
10. Hepatitis C, and other bloodborne diseases
11. Skin or soft tissue infections
12. Scarring or collapsed veins
Even those who use cocaine without a needle put themselves at danger for HIV because cocaine clouds judgment, which can result in unsafe sexual conduct with infected partners.
According to studies, using cocaine hastens HIV infection. Cocaine affects immune cell performance and encourages HIV viral multiplication, according to study.
Additionally, studies show that those who use cocaine and have HIV may be more prone to acquiring other infections, such as the liver-damaging hepatitis C virus.
Reference: NIH
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